Tolerisation therapy for coeliac disease

The problem with a gluten free diet is that it’s hard to follow and trace amounts are everywhere, according to Leslie Williams, president of ImmunosanT. ImmunosanT is developing a tolerisation therapy for coeliac disease. People with this autoimmune disease suffer damage to their small intestines when they eat wheat, barley, rye or oats. Currently the only known treatment for coeliac disease is a strict lifelong gluten free diet. But a tolerisation therapy could make it possible for coeliacs to eat whatever they want. Read More »


How much gluten is safe for coeliacs?

Currently the only treatment for coeliac disease is a strict lifelong gluten free diet. However several studies have shown that bowel damage persists in a significant proportion of treated coeliac patients even though their symptoms are resolved. Accidentally or deliberately, they must be consuming small amounts of gluten.

One study of coeliac patients’ intestines had to reject 4 of their 49 volunteers because their intestines were abnormal. Led by Professor Alessio Fasano from the University of Maryland, the study fed coeliac patients tiny amounts of gluten as pills. Read More »

So how intolerant are you?

It seems to be the question on every waiter’s lips when you ask them about the ingredients in a dish. To the person with a food intolerance, it’s a sensible question. But imagine the mother of an allergic child, carrying an epipen in her handbag, or a coeliac who knows that one hundredth of a slice of bread can damage their bowel. These three people could all become sick from eating the wrong foods, but the reasons for it are quite different. Read More »